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Click on the phrases to see them in context. The original texts by Immanuel Kant and David Hume are available from the Gutenberg Projet.

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But where will he find the knowledge which can enable him to enounce synthetical judgements in regard to things which transcend the region of experience?

 When we receive any matter of fact upon human testimony, our faith arises from the very same origin as our inferences from causes to effects, and from effects to causes; nor is there anything but our experience of the governing principles of human nature, which can give us any assurance of the veracity of men. This latter connexion is generally much over-rated, and commands our assent beyond what experience will justify; which can proceed from nothing beside the resemblance betwixt the ideas and the facts. It teaches us to consider this refusal of our reason to give any satisfactory answer to questions which reach beyond the limits of this our human life, as a hint to abandon fruitless speculation; and to direct, to a practical use, our knowledge of ourselves--which, although applicable only to objects of experience, receives its principles from a higher source, and regulates its procedure as if our destiny reached far beyond the boundaries of experience and life. What this basis of cosmical unity may be in itself, we know not--we cannot discover from the idea; we merely know how we ought to employ the idea of this unity, in relation to the systematic operation of reason in the sphere of experience. For a question regarding the constitution of a something which cannot be cogitated by any determined predicate, being completely beyond the sphere of objects and experience, is perfectly null and void.] For example, the proposition, "Every change has a cause," is a proposition a priori, but impure, because change is a conception which can only be derived from experience. Of these it is impossible to present an intelligible conception; they are a kind of monogram, drawn according to no determinate rule, and forming rather a vague picture--the production of many diverse experiences--than a determinate image. 
Inasmuch as the substances in the world have always existed--at least the unity of experience renders such a supposition quite necessary--there is no difficulty in believing also, that the changes in the conditions of these substances have always existed; and, consequently, that a first beginning, mathematical or dynamical, is by no means required.
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