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Click on the phrases to see them in context. The original texts by Immanuel Kant and David Hume are available from the Gutenberg Projet.

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I know no investigations more necessary for a full insight into the nature of the faculty which we call understanding, and at the same time for the determination of the rules and limits of its use, than those undertaken in the second chapter of the "Transcendental Analytic," under the title of "Deduction of the Pure Conceptions of the Understanding"; and they have also cost me by far the greatest labour--labour which, I hope, will not remain uncompensated.

 The speculative part of metaphysic, which has especially appropriated this appellation--that which we have called the metaphysic of nature--and which considers everything, as it is (not as it ought to be), by means of a priori conceptions, is divided in the following manner. If, on the other hand, we were to ask Priestley--a philosopher who had no taste for transcendental speculation, but was entirely devoted to the principles of empiricism--what his motives were for overturning those two main pillars of religion--the doctrines of the freedom of the will and the immortality of the soul (in his view the hope of a future life is but the expectation of the miracle of resurrection)- this philosopher, himself a zealous and pious teacher of religion, could give no other answer than this; I acted in the interest of reason, which always suffers, when certain objects are explained and judged by a reference to other supposed laws than those of material nature--the only laws which we know in a determinate manner. The very nature and essence of chance is a negation of causes, and the leaving the mind in a perfect indifference among those events, which are supposed contingent. 
We then see how it does not involve any contradiction to assert, on the one hand, that the will, in the phenomenal sphere--in visible action--is necessarily obedient to the law of nature, and, in so far, not free; and, on the other hand, that, as belonging to a thing in itself, it is not subject to that law, and, accordingly, is free.
 But besides that this interest is only more immediate in the execution of justice among their subjects; besides this, I say, we may often expect, from the irregularity of human nature, that they will neglect even this immediate interest, and be transported by their passions into all the excesses of cruelty and ambition.. If we admit the existence of spontaneously produced events, that is, of free agency, we are driven, in our search for sufficient reasons, on an unavoidable law of nature and are compelled to appeal to the empirical law of causality, and we find that any such totality of connection in our synthesis is too small for our necessary empirical conception. The highest reality must be regarded rather as the ground than as the sum-total of the possibility of all things, and the manifold nature of things be based, not upon the limitation of the primal being itself, but upon the complete series of effects which flow from it. And though we must endeavour to render all our principles as universal as possible, by tracing up our experiments to the utmost, and explaining all effects from the simplest and fewest causes, it is still certain we cannot go beyond experience; and any hypothesis, that pretends to discover the ultimate original qualities of human nature, ought at first to be rejected as presumptuous and chimerical.